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    • Our Story
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    • Partnership
  • GMP MANUFACTURING
  • Solutions
    • J.DESIGN
      • Humanoid Antibody Library (J.HAL)
      • GMP Manufacturing (J.POD)
  • News
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    • Publications
      • Drug Discovery Update (DDup) journal
      • Scientific journals
    • Webinars
    • White Papers & Application Notes
  • Careers
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  • Evotec

Publications

Automated multi-attribute method sample preparation using high-throughput buffer exchange tips

Scientific journalsDecember 17, 2021

In recent years, the multi-attribute method (MAM) has become an important mass spectrometry-based tool for identifying and quantifying the site-specific product attributes and purity information…

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Development of recombinase-based targeted integration systems for production of exogenous proteins using transposon-mediated landing pads

Scientific journalsOctober 26, 2021

Journal: Current Research in Biotechnology (CRBIOT)

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Evotec publishes DDup 11 – AI-driven antibody discovery at Evotec

Scientific journalsSeptember 15, 2021

The 11th edition is dedicated to our exciting new capabilities in the biologics lane of Evotec’s “Multi-modality Autobahn.” For the biologics industry, Evotec provides a…

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Introduction to antibodies

Introduction to Antibodies

DDup 11September 15, 2021

What are antibodies? Antibodies, or immunoglobulin molecules, are glycoproteins produced by the plasma B cells of the adaptive immune system with the aim to recognise…

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AI-driven antibody discovery

AI-driven antibody discovery at Evotec

DDup 11September 15, 2021

Antibody discovery may be driven by the interrogation of two primary sources: (1) in vivo (animal-derived B cells) or (2) in vitro (library-derived antibody display…

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FFmab

Function-focused antibody (FFmab) screening

DDup 11September 15, 2021

What is FFmab screening? FFmab screening is a platform for identifying novel functional antibodies that change disease-modifying phenotypes of immune cells. The platform identifies innovative…

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Karen Lackey and Jim Thomas

Interview with Dr Jim Thomas and Karen Lackey

DDup 11September 15, 2021

What role do Biologics play in the context of novel therapeutics? Jim: Biologics are a significant and growing portion of the arsenal of therapeutics used…

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Barbara Bachler-Konetzki

Interview with Barbara Bachler-Konetzki about Evotec’s integrated antibody discovery capabilities

DDup 11September 15, 2021

What were the limitations of previous hybridoma-based approaches? Although the development of the hybridoma technology was a landmark event, the methodology still faced the limitation…

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Randall Ketchem

Interview with RANDAL R. KETCHEM about the optimization of antibodies

DDup 11September 15, 2021

How does optimization of antibodies improve development? Just – Evotec Biologics has developed a molecular optimisation platform for monoclonal antibodies to increase productivity, eliminate potential…

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Biologics manufacturing without the big bioreactors

Scientific journalsSeptember 28, 2020

Producing therapeutic antibodies is expensive and difficult, but drug-makers have unprecedented flexibility in plant design through a new modular biologics manufacturing platform that streamlines the…

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Designing Feature-Controlled Humanoid Antibody Discovery Libraries Using Generative Adversarial Networks

Publications, Scientific journalsApril 13, 2020

Just – Evotec Biologics has compiled a library of a new class of humanoid antibodies using a novel, AI-derived approach. Antibodies are proteins produced and…

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Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity

Publications, Scientific journalsJanuary 1, 2020

Journal of Pharmaceutical Sciences

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