DDup 11 – AI-driven antibody discovery at Evotec

What are antibodies? Antibodies, or immunoglobulin molecules, are glycoproteins produced by the plasma B cells of the adaptive immune system with the aim to recognise…

Antibody discovery may be driven by the interrogation of two primary sources: (1) in vivo (animal-derived B cells) or (2) in vitro (library-derived antibody display…

What is FFmab screening? FFmab screening is a platform for identifying novel functional antibodies that change disease-modifying phenotypes of immune cells. The platform identifies innovative…

What role do Biologics play in the context of novel therapeutics? Jim: Biologics are a significant and growing portion of the arsenal of therapeutics used…

What were the limitations of previous hybridoma-based approaches? Although the development of the hybridoma technology was a landmark event, the methodology still faced the limitation…

How does optimization of antibodies improve development? Just – Evotec Biologics has developed a molecular optimisation platform for monoclonal antibodies to increase productivity, eliminate potential…