Randal R. Ketchem, Ph.D.
Dr. Randal Ketchem received his Ph.D. in Molecular Biophysics from Florida State University, focusing on experimental protein structure determination, resulting in the first membrane-bound protein structure solved by Solid State NMR. As part of this effort, he developed computational methods for the structure calculation and refinement of membrane-bound proteins. Randy continued his training in structural biology in a postdoctoral fellowship at The Scripps Research Institute where he expanded his experimental and computational efforts into solution-based protein structure. Randy then joined Immunex in 1997 to apply his expertise in protein structure modeling and analysis, to efforts in the development of biologic-based therapeutics.
During his many years of experience at Immunex, Amgen, Just Biotherapeutics, and Just – Evotec Biologics he has led efforts to engineer protein therapeutics, invented novel therapeutic modalities and computational methods for therapeutic design, and developed computational and experimental approaches to understanding and controlling biophysical properties of biological macromolecules. Randy has made significant contributions in antibody design, epitope mapping, molecular assessment, stability engineering, construct design, protein structure analysis, and protein engineering. At Just, Randy leads J.MD, incorporating biologics design and optimization, informatics development, Data Science, and J.HAL antibody discovery.